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46 Liver disease In a 72-week phase 2 study of patients (n = 320) with metabolic dysfunction-associated steatohepatitis (MASH), semaglutide (0.1, 0.2 or 0.4 mg daily) reduced steatosis but had no effect on fibrosis

Overall, a new era in obesity care is starting, as multiple effective obesity pharmacotherapies with different mechanisms of action and routes of administration may become available over next years

Others prefer starting directly with tirzepatide for its superior efficacy data